San Francisco 49ers quarterback Jimmy Garoppolo didn't practice again Friday and is officially doubtful with a right thumb injury, but coach Kyle Shanahan said he's "not ready to announce" that Trey Lance will start Sunday against the Texans.

Garoppolo doubtful, but 49ers ‘holding out hope’

San Francisco 49ers quarterback Jimmy Garoppolo didn't practice again Friday and is officially doubtful with a right thumb injury, but coach Kyle Shanahan said he's "not ready to announce" that Trey Lance will start Sunday against the Texans.